Developmental Anomalies of the Eye Lens

 Developmental Anomalies of the Lens

Anomalies of lens shape are very rare. Lenticonus is a circumscribed conical protrusion of the anterior pole (anterior lenticonus) or posterior pole (poste-rior lenticonus). A hemispherical protrusion is referred to as lentiglobus. Symptoms include myopia and reduced visual acuity. Some patients with Alport’s syndrome (kidney disease accompanied by sensorineural hearing loss and anomalies of lens shape) have anterior lenticonus. Posterior lenti-conus may be associated with a lens opacity (Fig. 7.6). Treatment is the sameas for congenital or juvenile cataract.


Microphakia refers to a lens of abnormally small diameter. Any interrup-tion of the development of the eye generally leads to microphakia. This can occur for example in Weill-Marchesani syndrome (see Table 7.5).







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